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The origin of Sven Furberg’s 3-Dimensional nucleotide was crucial to the resolution of the Watson and Crick structure.



    “Furberg, reasoning with marked brilliance and luck from data that were meagre but included his own X-ray studies, got right the absolute three-dimensional configuration of the nucleotide: where Astbury had set sugar parallel to base, Furberg, in what he called the the standard configuration, set them at right angles.  As a structural element, that standard configuration was a powerful help.  “Furberg’s nucleotide - correcting Astbury’s error - was absolutely essential to us,” Crick told me.”


Horace Freeland Judson - The Eighth Day of Creation (p115)


    “Considering the techniques of those days, Furberg’s solution of this molecule’s 3-dimensional structure based on 2-dimensional Fourier projections was “a very remarkable piece of work.  It was in fact such a difficult problem that if he had asked advice he would have been told that it was not possible to solve it” (Crick, 1973).”


Robert Olby - The Path to the Double Helix (p337)



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